Experts in Particle Characterization

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Sample Characterization Services

Professional Analytical Services

Overview

Brookhaven Instruments is now pleased to offer sample characterization services of your nanoparticles, proteins and polymers. A pioneer in the field with over 30 years of expertise, our team of application scientists will measure physical properties of your materials including:

  • Particle/Protein Size
  • Zeta Potential (Surface Charge)
  • Molecular Weight (Mn, Mw, Mz)
  • Differential Refractive Index
  • Dielectric Constant
  • Dynamic Viscosity of Fluids
 

Particle/Protein Size

Particle Size

Dynamic Light Scattering

correlation function

  • DLS measurements conform to international
    standards, ISO 13321 & ISO 22412
  • Range > 1 nm to 6 µm
  • Available measurement angles: 15°, 90° or 173° (backscatter)
  • Small volume of only a few µL needed
  • -5 °C to +110 °C temperature range
  • Accurate & repeatable size average (RHEffective Diameter, Z-Average) and polydispersity information
  • Report includes assessment of particle size 
    populations and their respective sizes
  • Size distribution information available by 
    Intensity, Volume, Surface Area, and Number
  • Multi-angle Goniometer for advanced sample analysis
  • Particle size as a function of additive concentration

Examples:

  • Polymer latex
  • Nanoparticles
  • Micelles & Liposomes
  • Proteins
  • Pharmaceutical preparations
  • Emulsions
  • Paints & pigments
  • Inks and toners

Disc Sedimentation

DCP Distribution

  • Offers superior resolution of complex particle size distributions when DLS alone doesn't suffice
  • Obtain the full size distribution by measuring slice in time of particle sedimentation under high gravity
  • Suitable for a wide range of sizes and densities
  • Yields the highest resolution of tailing, asymmetric distributions and closely spaced populations
  • Reports offer detailed distribution & width information by 
    Volume (mass), Number, and Surface Area

Examples:

  • Polymer latexes
  • Nano-dispersions
  • Carbon blacks
  • Metal oxides, refactories
  • Ink particulates, alumina, titania
  • Pharmaceuticals, cosmetics, foods
  • Coatings, paints
  • Encapsulated systems
  • Protein-loaded microcapsules
  • PLGA shell - delivery
  • Emulsion polymer

Zeta Potential

Zeta Potential (Surface Charge)

Zeta Potential Phase

  • Determine stability of colloidal suspensions
  • Aqueous
  • Organic solvents
  • Oily or viscous media
  • Proteins
  • High salt suspension
  • Near the IEP
  • Isoelectric point determination (point of zero charge)
  • Zeta Potential as a function of additive concentration

Examples

  • Lipsomes and bio-colloids
  • Ceramics and refactories
  • Pigments and inks
  • Pharmaceuticals
  • Emulsions (foodstuffs, comestics
  • Wastewater treatment monitoring
  • Latexes
  • Carbon blanks

Molecular Weight

Molecular Weight & Static LightChromatogram Scattering

Chromatogram

  • GPC/SEC Chromatography
  • Determine: Mn, Mw, Mz, Rg, A2
  • Zimm, Berry, Debye, Guinier, Kratky Plots

Zimm Plot

Differential Refractive Index

Differential Index of Refraction

Dn/Dc

  • dn/dc
  • Proteins
  • Polymers in aqueous & organic solvents
  • Measurement of sample up to 80 °C
 

Dielectric Constant

Dielectric Constant

BI-870

  • Solvents
  • Oils
  • Diesel Fuel Impurities
  • Mixed Liquids

Viscosity

Viscosity

SV-10
  • 0.3 to 10,000 cP
  • 1% accuracy and repeatability
  • Reduce errors in DLS and zeta potential results due to incorrect dispersant viscosity
 
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