Experts in Particle Characterization


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NanoBrook ZetaPlus Zeta Potential Analyzer

Zeta Potential Analyzer


NanoBrook ZetaPlusFeatures at a glance

  • Zeta potential in low salt aqueous solutions/suspensions
  • Accurate, rapid, easy to make zeta potential determinations
  • One piece, easy-fill disposable sample cells
  • No cell alignment or calibration
  • Zeta potential at 15°
  • Temperature control, -5 °C to 110 °C
  • Customizable reports, two parameter plots, graphical overlays
  • Can resolve multi-modals
  • Built in automatic procedures and parameters SOP
  • Reliable, Accurate, and Accurate Analysis

    The NanoBrook ZetaPlus is the simplest and most accurate particle electrophoresis system available. This revolutionary instrument has been designed to eliminate the short coming inherent in other zeta potential instruments. The ZetaPlus software is simple and intuitive to operate but yet offers flexibility and a full range of means for those that whish to tune their experiments to specific circumstances.

    The screen image shown below indicates the clear and concise presentation. Information obtained from the sample is updated in real time and the user can select from several display formats. A table of physical constants for many common suspending fluids is provided but the user may provide their own values if desired. Printed reports are fully customizable.

    Zeta Potential with Particle Solutions

    Comprehensive Information

    The NanoBrook ZetaPlus measures complete electrophoretic mobility distributions in seconds including multimodals (an example of bimodal zeta potential sample can be seen on the result screen from analyzing a mixture of charged particles.)

    In the example below the result of analyzing a mixture of alpha and gamma Aluminas in 1 mMolar KCI at pH10 is displayed. The left peak is identified with the green cursor and shown to have a zeta potential of -75 mV. If the other peak is chosen the value given is -5.00 mV. The ability of the NanoBrook ZetaPlus to provide this information distinguishes it from other methods which provide only an ensemble average.

    Zeta Potential bimodal

    Derive Extended Information

    The user can tabulate or graph any appropriate pair of parameters allowing, for example, the determination of the iso-electric point (IEP) as in the example below. The NanoBrook ZetaPlus is provided with a pH probe.

    Isoelectric point with Particle Solutions

    Unique Cell Design

    The unique cell configuration eliminates the electroosmotic effect: No stationary levels, no alignment, and no calibration are required; as evidenced by the excellent agreement with NIST1980, a standard reference material. The NanoBrook ZetaPlus uses low cost, disposable sample cells. There is no assembly or maintenance required: Cross contamination is eliminated. Glass and quartz cells are available optionally. The same basic cell design is used with the NanoBrook 90Plus Zeta, ZetaPALS, 90Plus PALS, and Omni.

    Typical Applications

    Typical Applications

  • Liposomes and biocolloids
  • Ceramics and refractories
  • Pigments and inks
  • Pharmaceuticals
  • Emulsions (foodstuffs, cosmetics)
  • Wastewater treatment monitoring
  • Latexes
  • Carbon blacks
  • Specifications


    Sample Type Most nanoparticle, polymer and colloidal-sized materials, suspended in any non-absorbing liquid, with relative permittivity (dielectric constant) > 20 and viscosity < 5 cP
    Size Range 1 nm to 100 µm diameter, sample dependent
    Mobility range 10-9 to 10-7 m2 / V * s
    Zeta potential range -220 mV to 220 mV, sample dependent
    Sample cells 180 µL, 600 µL, 1250 µL
    Maximum sample concentration 40% v/v, sample dependent
    Maximum sample conductivity 7.5 mS/cm
    Signal processing Electrophoretic Light Scattering, ELS
    Precision ± 3%, depending on salt concentration
    Temperature control range -5 °C to 110 °C ± 0.2 °C
    Condensation control Purge facility using dry air, nitrogen preferred
    Standard laser 40 mW red diode laser, nominal 640 nm wavelength
    Scattering angle 15°
    Data Presentation Doppler Frequency Shift, electrophoretic mobility, zeta potential suing Smoluchowski Hückel, or Henry
    Power Requirements 100/115/220/240 VAC, 50/60 Hz, 150 Watts
    Diemensions 23.3 x 42.7 x 48.1 cm (HWD)

    15 kg

    Environmental Characteristics

    Temperature 10 °C to 75 °C

    Humidity 0% to 95%, non-condensing

    CE certification Class I laser product, EN 60825-1:2001, CDRH

    Options & Accessories


    BI-ZTU Autotitrator, 4-pump, pH, temp, conductance for use with acids, bases, surfactants, dispersing agents, salts and other additives to determine the IEP and trend of zeta potential with concentration of additive. BI-ZTU includes one BI-ZELF and one BI-ZELF-B for use with aqueous samples.
    BI-ZELF Plastic electrode assembly for use with BI-ZTU in flow mode, including one BI-ZELF-B
    BI-ZELF-B Box of 2 plastic flow cells for use with BI-ZELF
    BI-870 Dielectric constant meter improves accuracy when calculating zeta potential in solvent mixtures and specialty solvents.
    BI-IQOQPQ Qualification for installation, operation and performance.


    BI-SCP Box of 100 plastic cells, use with BI-ZEL electrode assembly and aqueous samples.
    BI-SVE175 Electrode assembly for aqueous systems, with BI-SCP cell, 175 µL sample volume.
    BI-ELECCK Electrode cleaning kit including wand and polishing strip, for use with BI-ZEL and BI-SREL
    BI-CC Nitrogen-purge facility for condensation control.
    BI-SCP Box of 100 plastic cells, use with 1.25 mL, 600 µL, and 180 µL assemblies and aqueous solutions and suspensions.
    BI-ZR5 Zeta reference material for validation, blue pigment for use in water, -(44 ± 8)mV.

    Note: Current users of the ZetaPlus may upgrade to include PALS and particle sizing including backscatter provided their instrument has the necessary mechanics, optics and hardware. Contact the factory for more information.

    Download Brochure

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